Addition reactions to multiple C-C bonds

Addition reactions to multiple C-C bonds take place when a functional group is added to a carbon-carbon double (C=C) or triple (C≡C) bond, reducing their bond order.

This section lists the most significant named organic reactions classified according to the type of chemical reaction. Among the named organic reactions of the addition type to multiple C-C bonds we can highlight the following:

Benkeser reduction

Benkeser reduction

References:
R.A. Benkenser et al., J. Am. Chem Soc. 74, 5699 (1952)

Birch reduction

Birch reduction

References:
A.J. Birch, J. Chem. Soc. 1944, 430
A.J. Birch, J. Chem. Soc. 1945, 809
A.J. Birch, J. Chem. Soc. 1946, 593
A.J. Birch, J. Chem. Soc. 1947, 102
A.J. Birch, J. Chem. Soc. 1947, 1642
A.J. Birch, J. Chem. Soc. 1949, 2531

Diels-Alder reaction

Eltekoff reaction

Eltekoff reaction

References:
A. P. Eltekoff, Chem. Ber. 11, 412 (1878)
A. P. Eltekoff, Chem. Ber. 16, 395 (1863)
A. P. Eltekoff, J. Russ. Phys. Chem, Soc. 10, 86 (1878)
A. P. Eltekoff, J. Russ. Phys. Chem, Soc. 14, 355 (1882)

Ene Reaction (Alder-Ene Reaction)

Ene Reaction (Alder-Ene Reaction)

References:
K. Alder, F. Pascher, A. Schmitz, Chem. Ber. 76, 27 (1943)

Ferrario-Ackermann reaction

Ferrario-Ackermann reaction

References:
F Ferrario. Bull. Soc. Chim. France 9, 536 (1911)
F. Ackermann, Ger. Patent 234, 743 (1910)

Janovsky reaction

Janovsky reaction

References:
J.V. Janovsky, L. Erb, Chem. Ber. 19, 2155 (1886)

Koch-Haaf carboxylation

Koch-Haaf carboxylation

References:
H. Koch, Brennstoff Chem. 36, 321 (1955)

Kucherov reaction

Kucherov reaction

References:
M. Kucherov, Chem. Ber. 14, 1540 (1881)

Levinstein process

Levinstein process

References:

Milas hydroxylation of Olefins

Milas hydroxylation of Olefins

References:
N.A. Milas, S. Sussmann, J. Am. Chem. Soc. 58, 1302 (1936)
N.A. Milas, P.F. Kurz, W.P. Anslow Jr., J. Am. Chem. Soc. 59, 543 (1937)
N.A. Milas, J. Am. Chem. Soc. 59, 2342 (1937)
N.A. Milas, S. Sussmann, J. Am. Chem. Soc. 59, 2345 (1937)
N.A. Milas, S. Sussman, H.S. Mason, J. Am. Chem. Soc. 61, 1844 (1939)

Mukaiyama aldol addition

Mukaiyama aldol addition

References:
T. Mukaiyama et al., Chem. Lett. 1973, 1011
T. Mukaiyama et al., Chem. Lett. 1974, 323
T. Mukaiyama et al, J. Am. Chem. Soc. 96, 7503 (1974)

Nazarov cyclization reaction

Nazarov cyclization reaction

References:
I. N. Nazarov, I. B. Torgov and L. N. Tcrckhova, Izo. Akad. Nauk S.S.S.R., Otd. Khim. Nauk 1942, 200.
I. N. Nazarov et al., Izv. Ahad. Nauk S.S.S.R., Otd. Khim. Nauk 1943, 389; 1945, 65; 1946, 529,633; 1947, 205, 277, 353, 495, 647

Nenitzescu reductive acylation

Nenitzescu reductive acylation

References:
C.D. Nenitzescu, E. Cioranescu, Chem. Ber. 69, 1820 (1936)
C.D. Nenitzescu, C.N. Ionescu, Ann. 491, 189 (1931)
C.D. Nenitzescu, I. Chicos, Chem. Ber. 68, 1584 (1935)

Paternò-Büchi reaction

Reacción de Paterno-Büchi

References:
E. Paternò, G. Chieffi, Gazz. Chim. Ital. 39, 341 (1909)
G. Büchi, C. G. Inman, E. S. Lipinsky, J. Am. Chem. Soc. 76, 4327 (1954)

Pauson-Khand reaction

Pauson-Khand reaction

References:
I.U. Khand et al., J. Chem. Soc. Perkin trans. I 1973, 977

Pellizzari reaction

Pellizzari reaction

References:
G. Pellizzari, Gazz. Chim. Ital. 41, II, 20 (1911)

Prévost reaction

Prévost reaction

References:
C. Prévost, Compt. Rend. 196, 1129 (1933)
M. Sletzinger, C.R. Dawson, J. Org. Chem. 14, 670 (1949)

Prilezhaev reaction

Prilezhaev reaction

References:
N. Prileschajew, Chem. Ber. 42, 4811 (1909)

Sakurai reaction (Hosomi-Sakurai reaction)

Sakurai reaction (Hosomi-Sakurai reaction)

References:
A. Hosomi, H. Sakurai, Tetrahedron Lett. 1976, 1295
A. Hosomi, M. Endo, H. Sakurai, Chem Letters 1976, 941

Sharpless asymmetric dihydroxylation

Sharpless asymmetric dihydroxylation

References:
E.N. Jacobsen, I. Marko, W.S. Mungall, G. Schroeder, K.B. Sharpless, J. Am. Chem. Soc. 110, 1968 (1988)

Sharpless epoxidation

Sharpless epoxidation

References:
T. Katsuki, K.B. Sharpless, J. Am. Chem. Soc. 102, 5974 (1980)
S.S. Woodward, M.G. Finn, K.B. Sharpless, J. Am. Chem. Soc. 113, 106 (1991)
M.G. Finn, K.B. Sharpless, J. Am. Chem. Soc. 113, 113 (1991)

Sharpless oxyamination

Sharpless oxyamination

References:
K.B. Sharpless et al., J. Am. Chem. Soc. 97, 2305 (1975)
L. Mangatal et al., Tetrahedron 45, 4177 (1989)
S. K. Dudey, E. E. Knaus, Can. J. Chem. 61, 565 (1983)
M. Lemaire et al, Synlett 1990, 615

Simmons-Smith reaction

References:
H.E. Simmons, R.D. Smith, J. Am. Chem. Soc. 80, 5323 (1958)
H.E. Simmons, R.D. Smith, J. Am. Chem. Soc. 81, 4256 (1959)
R.S. Schlank, H. Schechter, J. Org. Chem. 24, 1825 (1959)
R.D. Smith, H.E. Simmons, Organic Syntheses 41, 72 (1961)

Wagner-Jauregg reaction

References:
T. Wagner-Jauregg, Chem. Ber, 63, 3213 (1930)
T. Wagner-Jauregg, Ann. 491, I (1931)

Woodward cis-hydroxylation

Woodward cis-hydroxylation

References:
R.B. Woodward, U.S. Patent 2687435 (1954)
R.B. Woodward, F.V. Brutcher, J. Am. Chem. Soc. 80, 209 (1958)

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