Aliphatic electrophilic substitution reactions

Aliphatic electrophilic substitution occurs with the displacement of an electrophile to an alkyl functional group. Several mechanisms have been described (SE1, SE2 y SEi).

In this section, the most significant named organic reactions are listed, classified according to the type of chemical reaction. Among the named organic reactions of the aliphatic electrophilic substitution type we can highlight the following:

Dakin-West reaction

Dakin-West reaction

References:

H.D. Dakin, R. West, J. Biol. Chem. 78, 91, 745, 757 (1928)
J. Attenburrow et al J. Chem. Soc., 310 (1948).
Cleland, Niemann, J. Am. Chem. Soc. 71, 841 (1949)

Haller-Bauer reaction

Haller-Bauer reaction
Haller-Bauer reaction
Haller-Bauer reaction

References:

A. Haller, E. Bauer, Compt. Rend, 148, 70,127(1909); 149,5(1909);
Ann. Chem, I, 5(1914)
A. Haller, Bull, Soc. Chim, France 31, 1117(1922)
A. Schonberg, Ber, 58, 580(1925)

Hell-Volhard-Zelinsky halogenation

Hell-Volhard-Zelinsky halogenation

References:

C. Hell, Ber. 14, 891 (1881); J. Volhard, Ann. 242, 141 (1887)
N. Zelinsky, Ber. 20, 2026 (1887)

Japp-Klingemann reaction

Japp-Klingemann reaction

References:

F. R. Japp and F. Klingernann, Ann. 247, 190 (1888); Ber. 20, 2942, 3284, 3398 (1887).
R. P. Linstead and A. Wang, J. Chem. Soc., 807 (1937).
R. L. Frank and R. R. Phillips, J. Am. Chem. Soc. 71, 2804 (1949)

Stork enamine alkylation and acylation reactions

Stork enamine alkylation and acylation reactions

References:

G. Stork, R.ltertell and J. Szmuszkovicz, J. Am. Chem. Soc. 76, 2029 (1954)
G. Stork and H. Landesman, J. Am. Chem. Soc., 78, 5128 (1956)
M.E. Kuchne, J. Am. Chem. Soc. 84, 837 (1962)

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