Aliphatic Electrophilic Substitution Named Reactions

What are aliphatic electrophilic substitution name reactions?

Aliphatic electrofilic substitution is a type of organic reaction where an electrophile (electron-poor species) replaces a leaving group on an aliphatic compound. Several mechanisms have been described (SE1, SE2 y SEi).

SE1 (Substitution Electrophilic Unimolecular) reactions are the simplest type of aliphatic electrophilic substitution reactions. In this reaction, the target molecule undergoes substitution through a one-step process, in which the electrophile attacks the target molecule, replacing a leaving group. SE1 reactions typically involve tertiary carbon centers and carbocations, which are intermediate species in the reaction. The reaction rate of SE1 reactions is highly dependent on the stability of the carbocation intermediate..

SE2 (Substitution Electrophilic Bimolecular) reactions are a type of aliphatic electrophilic substitution that involve two steps. In the first step, the electrophile attacks the target molecule, forming a complex intermediate. In the second step, the leaving group departs, leading to the formation of the final product. SE2 reactions are typically characterized by intermediate species that are not carbocations, such as aryl or alkyl anions. The reaction rate of SE2 reactions is dependent on the concentration of both the electrophile and the nucleophile..

SEi (Substitution Electrophilic Inner-Sphere) reactions are a type of aliphatic electrophilic substitution that are similar to SE2 reactions, but the intermediate species is a complex between the electrophile and the nucleophile, rather than a carbocation or anion. In SEi reactions, the electrophile and the nucleophile interact with each other to form a complex, which then reacts with the target molecule to form the final product. The reaction rate of SEi reactions is dependent on the strength of the interaction between the electrophile and the nucleophile..

Electrophilic substitution reactions play a significant role in organic chemistry and are widely used in the synthesis of various organic compounds..

In this section, the most significant named organic reactions are listed, classified according to the type of chemical reaction. Among the named organic reactions of the aliphatic electrophilic substitution type we can highlight the following in the next table:

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