Elimination reactions

The elimination reaction occurs when two substituents leave the molecule to form an unsaturation, which can be a double bond, triple bond or ring. They occur through two types of unimolecular (E1) and bimolecular (E2) mechanisms.

A particular case of elimination reaction is when the two groups that are detached from the molecule belong to the same carbon, since it results in a carbene (:CR2).

In this section, the most significant named organic reactions are listed, classified according to the type of chemical reaction. Among the named organic reactions of the elimination type we can highlight the following:

Bamford-Stevens reaction

Bamford-Stevens reaction

References:
W. R. Bamford and T. S. Stevens, J. Chem. Soc. 1952, 4735

Boord olefin synthesis

Boord olefin synthesis

References:
L. C. Swallen and C. E. Boord, J. Am. Chem. Soc. 52, 651 (1930); 53, 1505 (1931); 55, 3293(1933)

Chugaev elimination

Método de Chugaev
Reacción de Chugaev

References:
L. Chugaev (Tschugaeff), Ber. 32, 3332 (1899)
F. C. Whitman and C. T. Simpson, J. Am. Chem. Soc. 55, 3809 (1933)
P. G. Stevens and J. H. Richmond, J. Am. Chem. Soc. 63, 3132 (1941)
C. H. Depuy, R. W. King, Chem. Rev. 60, 444 (1960)
H. R. Nace, Org. React. 12, 57 (1962)

Cope elimination

Cope elimination

References:
A. C. Cope, T. T. Foster and P. H. Towle, J. Am. Chem. Soc. 71, 3929 (1949)
J. Am. Chem. Soc. 75, 3212 (1953)

Corey-Winter Olefin Synthesis

Corey-Winter Olefin Synthesis

References:
E. J. Corey, R. A. E. Winter, J. Am. Chem. Soc. 85, 2677 (1963)
M. Tichy, J. Sicher, Tetrahedron Letters 1969, 4609

Eschenmoser fragmentation

Fragmentation de Eschenmoser

References:
A. Eschenmoser et al., Helv. Chem. Acta 50,708 (1967)
J. Schreiber et al., ibid. 2101
M. Tanabe et al. Tetrahedron Letters 1967, 3943
D. Felix et al., Helv. Chim. Actga 54 2896-2912 (1971)

Henry reaction (nitroaldol reaction)

Reacción de Henry o Reacción de Kamlet

References:
L. Henry, Compt. Rend. 120, 1265 (1895)
J. Kamlet, U.S. pat. 2, 151, 517 (1939); C.A. 33, 5003 (1939)
H. B. Hass and E. F. Riley, Chem. Revs. 32 406 (1943)

Hofmann elimination (exhaustive Hofmann methylation)

Degradación de Hofmann o etilación Exhaustiva de Hofmann

References:
A. W. Hofmann, Ber. 14, 659 (1881)
H. Gilman, Organic Chemistry ll (Ner York, 1943), p 1172
M. Pailer and L. Bilek, Monatsh. 79, 135 (1948)

Kuhn-Winterstein reaction

Kuhn-Winterstein reaction

References:
R. Kuhn and A. Winterstein, Helv. Chim. Acta 11, 87 (1928)
Kuhn et al., Ber. 71, 1510 (1938); 84, 566 (1938); 84, 566 (1961); 88, 309 (1955)

Ramberg-Bäcklund reaction

Ramberg-Bäcklund reaction

References:
L. Ramberg and B. Bäcklund, Arkiv. Kemi Mineral Geol. 13A (27), 50 (1940); C.A. 34, 4725 (1940)

Retro-DielsAlder reaction

Retro-Diels-Alder reaction

References:
K. Kwart, K. King, Chem. Rev. 68, 415-447 (1968)
O. Papies, W. Grimm, Teterahedron Letters 21, 2799 (1980)

Von Braun amide degradation

Von Braun amide degradation
Degradaciones de von Braun

References:

H. von Pechmann, Ber. 33, 611 (1900)
J. von Braun, Ber. 37, 3210 (1904)

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